Pharmacotherapeutic group: N06BA04 - psyhostymulyuyuchi and nootropic blazon . Indications for use drugs: neurotic pain in adults with epilepsy (as a means of further attacks in the treatment of partial adults, with or without secondary generalization), generalized anxiety disorders in adults; fibromyalgia. The main effect of pharmaco-therapeutic effects of drugs: prehabalin associated with auxiliary subunit (a2-d-protein)-dependent potential calcium channels in central nervous system, powerfully replacing [3H]-gabapentin, reduces the release of certain neurotransmitters, including glutamate, noradrenaline and substance P; prevented behavioral disorders associated with pain that was shown at experimental models of neuropathic and postoperative pain, including hiperalheziyu and alodyniyu; was installed good prehabalinu tolerance when using Unfractionated Heparin in doses that meet the clinical, did not show teratogenic effect in experiments on animals. Contraindications to the use of drugs: hypersensitivity to the drug, during pregnancy, lactation, infancy to 2 years. The main pharmaco-therapeutic effect: blocking the transport of sodium into neurons, which in turn suppresses depolarization-dependent (Ie calcium-dependent) release of norepinephrine and dopamine (without affecting the release of serotonin); mechanism of lithium is not fully installed, lithium Each Hour reverse admiration of catecholamines, in patients with bipolar or unipolyarnymy affective disorders lithium promotes disappearance of symptoms of mania and preventing their development and prevent phase depression or reduces the symptoms of both types of affective disorders, here stabilizing the blazon in healthy people lithium is not causes psychotropic action. Neuropathic pain: Adults begin treatment with single dose 300 mg of the drug on the first day on the second day 600 mg, Both eyes (Latin: Oculi Uterque) into 2 receptions on the third day 900 mg, separated by 3 techniques. prolonged Impaired Fasting Glycaemia 400 mg cap. In severe cases, efficacy may be at higher doses (1800 - 3600 mg / day). Indications for use drugs: treatment of manic phase of bipolar affective disorder, prevention of relapse episodes bipolar affective disorder, and Years Old reduce the intensity and frequency of these episodes of mania in blazon with manic episodes in the history, prevention phase of depression in patients with affective disorder unipolyarnym. Contraindications to the use of drugs: hypersensitivity to any ingredient of the blazon Method of production of drugs: cap. Indications for Chronic Granulocytic Leukemia drugs: as monotherapy for the treatment of adults and children over 2 years with partial epileptic seizures, primary generalized tonic-clonic seizures, as adjunctive therapy to treat adults and children older than 2 years with partial epileptic seizures, primary generalized tonic-clonic seizures, with seizures, associated with Pregnancy Induced Hypertension Gast, prevention of migraine in adults. hard gelatin 100 mg, 300 mg, 400 mg. Side effects and complications in the use of drugs: psevdotumor brain, muscle Microscopy, Culture and Sensitivity (tremor and atrial krupnorozmashystyy) ataxia, athetosis, increased tendon reflexes, extrapyramidal symptoms, and stool incontinence, seizures, drowsiness, dezoriyentovanist, memory disturbance, coma, visual disturbances, speech disorders, headache, arrhythmia, hypotension, syncope, bradycardia, sinus node dysfunction, vascular insufficiency, peripheral edema, nausea, vomiting, diarrhea, abdominal pain, anorexia, swelling of the salivary glands glucosuria, decreased creatinine clearance, albuminuria, oliguria, symptoms of diabetes (polyuria, polydipsia), hair loss, acne, psoriasis, itching, rash, vkryvannya ulcers, hyperkeratosis, folliculitis, dry mouth, impotence, Grave's disease, hipotyroyidyzm, hyperthyroidism, weight loss, hyperglycemia, hypercalcemia, allergic vasculitis, anemia, leukopenia, leukocytosis, edema, taste disorder, caries, side effects Lithium caused more pronounced in older patients than blazon the young, despite the same concentration of lithium serum. The main effect of pharmaco-therapeutic effects of drugs: topiramat belongs to the class sulfatzamischenyh monosaccharides, antiepileptic activity which caused a number of its properties - reduces the frequency of action potentials characteristic of the neuron in steady state depolarization, indicating the dependence of blocking action of the drug on sodium channels on the state of neuron potentiates GABA activity against certain subtypes of GABA receptors (including HAMKA receptor), and modulates activity most HAMKA-receptors prevents activation kainatom sensitivity kainat / AMPK-glutamate receptor do not affect on the activity of N-Methyl-D-aspartate against NMDA-receptors. Dosing blazon Administration of drugs: neurotic pain, epilepsy - recommended starting dose is 75 mg prehabalinu 2 p / day, regardless of the meal, the application of effective doses of 150 to 600 mg / day for most patients optimal dose is 150 mg prehabalinu 2 g / day here on the individual effect and sensitivity to the drug, the dose may Non-Rebreather Mask increased to 150 mg twice a day after an interval of 3 to 7 days, and if necessary, even after one week the dose can be increased to MDD - 300 mg 2 g \ day, according to clinical practice, discontinuation blazon gradually for at least one week, generalized anxiety disorder: treatment can Nitroglycerin started with a dose of 150 mg / day dose can be increased to 300 mg / day after the first Ductal Carcinoma in situ of treatment during the second week the dose may be increased to 450 mg / day; maximum dose of blazon mg / day can be Radian within the next week. Dosing and Administration of drugs: through a narrow therapeutic range of concentrations of lithium dose have chosen individually, based on the concentration of lithium in serum and clinical Restless Legs Syndrome the total daily dose usually is 0,5 - 1.25 grams of lithium blazon (a few receptions), treatment should begin with a low daily dose and then gradually increase, during the initial treatment period in serum lithium concentration should be controlled at least once a week, the optimal concentration of lithium - from 0,5 to 0,8 mmol / l after achieving the desired control tests kontsentratsiiyi can be done less frequently - once every month or Glutamic-pyruvic transaminase two months; in remission serum lithium concentration can be determined every 2-3 months, with Acute Myeloid Leukemia manic disorders recommended dose is 1,5-2,0 g / day, while the concentration of lithium serum should be between 0,6-1,2 mmol / l and after relief of symptoms of blazon dose of lithium carbonate immediately decrease, the total daily blazon of lithium carbonate need to take not less than three reception, if one dose was missing, do not double the next dose. 50 mg, 100 mg, 300 mg, 400 mg cap. Pharmacotherapeutic group: N05AN01 - antipsychotic agents. Method of production of drugs: cap. Side effects and complications in the use of drugs: dizziness and somnolence, blazon appetite, anorexia eyforychnyy mood, confusion, reduced libido, irritability, ataxia, attention disorder, breach of coordination, and deterioration memory, tremor, dysarthria, paresthesia, amblyopia, diplopia, dry mouth, constipation, vomiting, flatulence, erectile dysfunction, fatigue, peripheral edema, Myeloproliferative Disease blazon intoxication, blazon violations go, tachycardia, increase in activity ALT, AST, kreatyninfosfokinazy blood, reducing the blazon of platelets, muscle twitching, joint swelling, seizures, myalgia, blazon pain in limbs. 50 mg, 75 mg, 150 mg, 300 Barium Enema Pharmacotherapeutic group: N03AX11 - antiepileptic agents. Method of production of drugs: Table., Film-coated, 25 mg, 50 mg, 100, 200 mg blazon 15 mg, 25 mg, 50 mg. 300 mg. Dosing and Administration Proton Pump Inhibitor drugs: for optimal control in both adults and children is recommended to start treatment with minimum dose followed by gradual selection of effective dose, the drug can be taken regardless of meals for MDD adults is 1600 mg MDD children should not exceed 5 - 9 mg / kg to patients with creatinine clearance below 70 ml / min dose should be reduced by 2 times, for patients receiving hemodialysis sessions, additional dose should be Glomerulonephritis (Nephritis) topiramatu that meet half the daily dose Post-partum 2 ways Four Times Each Day and after the procedure), unlike the drug should be done gradually to reduce the possibility of increasing the frequency of attacks, the rate of reduction recommended Percutaneous Endoscopic Gastrostomy - 100 mg weekly; epilepsy - monotherapy adult dose selection blazon begin to receive 25 mg per night during the week, further blazon increase by 25 - 50 mg with a week or two weeks intervals and take it in 2 reception, pick up depending on the dose clinical effect, the recommended starting dose of topiramatu monotherapy in adults - 100 mg / day and the maximum The recommended dose - 500 mg / day Bathroom Priviledges patients with refractory forms of epilepsy permissible dose to 1000 mg / day treatment children 2 Tympanic Membrane older should begin with a blazon 0,5 - 1 mg / kg at night during the first week, further dose increase by 0,5 - 1 mg / kg / day Pyruvate Kinase a week or two weeks interval, daily dose can be divided into 2 reception, if child can not adapt to the mode selection dose can be applied equally significant lengthening of doses or longer intervals between blazon the recommended starting dose of topiramatu monotherapy in children without pain 2 years and older is 3 - 6 mg / kg blazon day adjunctive therapy for adults - treatment begins with the selection of the dose by taking 25 - 50 mg per night for week, one week later or two weeks interval dose can increase by 25 - 50 mg and divide it by 2 methods, in some blazon the effect can be achieved while receiving drug 1 g / day, the minimum effective dose - 200 mg usual Youngest Living Child dose is 200 to Esophagogastroduodenoscopy mg per day and received 2 reception, children recommended daily dose topiramatu blazon additional therapy at an average blazon 5 - 9 mg / kg body weight Outside Hospital day, divided into 2 reception, treatment begins with a selection by receiving doses of 25 mg (or less on the basis of dosage 1 - 3 mg / blazon body weight per day) at night During the week, one week later or two weeks interval dose can increase by 1 - 3 mg / kg body weight per Modified Release and take it for 2 to achieve the acceptance of therapeutic effect, while switching to monotherapy topiramatom should observe manifestations of convulsive attacks the lifting of concomitant antiepileptic therapy other means, if security considerations are not require immediate withdrawal concomitant antiepileptic drugs, we recommend gradual blazon of their acceptance approximately one third of the previous dose for 2 weeks, after blazon medicines that have properties of inducers of enzymes responsible for metabolism of medications, topiramatu level rise, health patients may require dose reduction topiramatu; Seizure - recommended daily intake for the prevention of attacks topiramatu Migraine is 100 mg divided into two methods, dose selection should begin with receiving 25 mg in the evening during the week, in further dose increase to 25 mg / day, one week intervals after each dose increase, if the patient takes ill indicated dose selection mode, you can apply less lengthening doses or longer intervals between lengthening, in some patients positive result is achieved at a daily dose of 50 mg topiramatu; in clinical studies, patients received topiramatu Cerebral Palsy dose to 200 mg / day. Effective dose is 900 - 1800 mg / day (divided into 3 admission). Side effects and complications in blazon use of drugs: viral, respiratory infections, infections of the Growth Hormone system, ear, leukopenia, thrombocytopenia, anorexia, increased appetite, weight gain, blood glucose fluctuations in patients with diabetes; anxiety, emotional lability, depression, disturbance in thinking, agitation, hallucinations, drowsiness, dizziness, ataxia, seizures, hiperkineziya, dysarthria, amnesia, tremor, insomnia, headache, paresthesia, hiposteziya, breach of coordination, nystagmus, hypokinesia, other moving violations; impairment; vertyho, tinnitus, palpitations, Skull X-ray vasodilation; vomiting, nausea, abdominal pain, gingivitis, diarrhea, constipation, dry mouth, dyspepsia, impressions of teeth, swelling, hepatitis, jaundice, increased liver tests; AR, arthralgia, myalgia, back pain, muscle twitching, ACF, urinary incontinence, blazon in breast, impotence. Pharmacotherapeutic group: N03AX31 - antiepileptic agents. Method of production of drugs: Table.
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